The Hagan Lab is seeking a highly motivated postdoctoral fellow to lead the computational analysis of multi-dimensional immune response data generated from human norovirus challenge studies. The fellow will integrate and analyze transcriptomic (RNA-seq), flow cytometry, cytokine, and serological datasets to define early innate immune signatures and identify predictors of adaptive immune responses. This position will involve applying statistical modeling and machine learning approaches to high-dimensional datasets, developing reproducible analysis pipelines, and collaborating closely with immunologists and clinical investigators. The ideal candidate will have a strong background in computational biology, bioinformatics, or a related field, with experience in omics data analysis and proficiency in programming languages such as R or Python. This is an excellent opportunity to contribute to systems immunology research with direct implications for vaccine development.
MAJOR DUTIES AND RESPONSIBILITIES:
* Develop the skills and knowledge (critical thinking and analysis of data, devising specific aims, long-term project planning and experimental design) to become an independent scientist
* Design, execute, and record laboratory experiments, and analyze data, which may affect decisions regarding future patient care.
* Research and improve current methods and evaluate innovative techniques. protocol and assay accuracy by conducting regular quality and reproducibility checks. Implement this knowledge in the Division/Department. Troubleshoot and correct erroneous results or problems with laboratory equipment.
* Discuss relevant insights about experimental results with Faculty and provide useful recommendations and analysis.
* Present research at laboratory meetings, journal clubs, seminars, and meetings. Develop skills to critically review and discuss data being presented.
* Draft, write, and edit scientific reports, papers, journal articles, abstracts, and grants.
* Progressively increasing responsibilities with mentorship of research staff and fiscal administration
* Maintain currency in field through continuing education, literature, and seminars. Be an active participant in the process through intellectual discussions with PI and other faculty, trainees and research staff. Solicit feedback on career trajectory from PI, mentoring committee and others who can provide coaching and insight.
* Attend required Cincinnati Children's training sessions and ensure regulatory compliance with all institutional (i.e. Infection Control, ORCRA and others as applicable) policies and procedures
* Perform other duties as assigned.
Required:
* PhD/MD or equivalent
Primary Location
Location S
Schedule
Full time
Shift
Day (United States of America)
Department
Infectious Diseases
Employee Status
Regular
FTE
1
Weekly Hours
40
About Us
At Cincinnati Children's, we come to work with one goal: to make children's health better. We believe in a holistic team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children's.
Cincinnati Children's is:
* Recognized by U.S. News & World Report as atop 10 best Children's Hospitals in the nation for more than 15 years
* Consistently among the top 3 Children's Hospitals for National Institutes of Health (NIH)Funding
* Recognized as one of America's Best Large Employers (2025), America's Best Employers for New Grads (2025)
* One
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